The Ozamiz Cathedral houses the city's most significant relic and patroness - the Our Lady of Misamis, also known as the Virgin sa Cotta, The Blessed Virgin of Cotta, and Birhen sa Cotta. Initially, the statue of the patroness was set up outside the walls of Fort sa Cotta, but Fray Jorge Carcabilla moved it to this church. 1975, the statue was stolen and returned on December 8, 2017. Also, Ozamiz Cathedral is the home of the second largest bamboo organ in the Philippines, after the Las Pinas Bamboo Organ.
